Russian scientists develop method to enhance effectiveness of anti-cancer medicines

Researchers in Russia said they have developed a new chemical method that could significantly improve the effectiveness of anti-cancer medicines by strengthening their active components.

The breakthrough was achieved by scientists at Lobachevsky State University of Nizhny Novgorod and focuses on enhancing biologically active compounds that suppress tumour cell growth.

The method enables the introduction of several aminomethyl groups into biologically active molecules.

These groups act as pharmacophore fragments that can amplify the therapeutic effect of anti-tumour drugs.

According to the research team, the approach allows such reinforcing elements to be added directly to existing pharmaceutical compounds, opening new possibilities for improving established treatments.

This is reported by the official website of Lobachevsky State University.

One of the key advantages of the technique is its efficiency. The synthesis delivers a product yield of around 90 per cent, while the purity of the resulting substance exceeds 95 per cent.

These parameters make the method promising for further development and potential application in large-scale pharmaceutical research and production.

In addition to strengthening known anti-cancer agents, the method is already being used to create previously unknown biologically active substances, including complex nitrogen-containing heterocycles that may have significant therapeutic potential.

The reaction also makes it possible to attach tumour-targeting peptides in a single step, which could improve the precision of future cancer therapies.